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Xi'an Jiaotong University

Project: Analysis of Mixture Composition through Peak Area and Position Calculation

Developed a 1D-CNN-based automated HPLC analysis system.

  • Model Architecture: Developed a 1D-CNN using PyTorch with an optimal configuration of 256 segments and input dimension of 8192 via hyperparameter tuning.
  • Signal Processing: Optimized the SNIP function for dynamic range compression and iterative peak suppression to mitigate baseline noise.
  • Data Engineering: Preprocessed real HPLC data and constructed a synthetic dataset comprising millions of samples.
  • Achievement: Achieved a Mean Relative Error (MRE) of under 3%, significantly outperforming traditional derivative methods and YOLO-based models.